Physiological and psychological effects of acute intentional hyperventilation.

Research is reviewed which suggests that hyperventilation syndrome is an underdiagnosed disorder for the presentation of many patients experiencing apparent anxiety states. In a test of this hypothesis, 21 normal individuals (9 female) underwent a 2 min period of intentional hyperventilation following a 10 min baseline phase. Hyperventilation was accompanied by increased subjective anxiety and tachycardia, and indications of peripheral vasoconstriction. Following hyperventilation, Ss experienced increased levels of state anxiety and perceived autonomic arousal, as indexed by self-report instruments. These results support the hypothesis that undiagnosed hyperventilatory phenomena may be etiologically implicated in states of pathologic anxiety.